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Steroids such as prednisone. Corticosteroids



 

Back to Health A to Z. Steroid tablets, also called corticosteroid tablets, are a type of anti-inflammatory medicine used to treat a range of conditions. They can be used to treat problems such as allergies , asthma , eczema , inflammatory bowel disease , Addison's disease and arthritis.

Steroid tablets are only available on prescription. Dissolvable, liquid and syrup versions are also available. Take your medicine as instructed by your doctor. They'll explain how much to take and how often. It's normally best to take steroid tablets with or soon after a meal — usually breakfast — because this can stop them irritating your stomach. If you forget a dose, take it as soon as you remember. If it's almost time for your next dose, skip the one you missed.

Accidentally taking too many steroid tablets is unlikely to be harmful if it's a one-off. Speak to your doctor or a pharmacist if you're worried. Taking too many steroid tablets over a long period can make you more likely to get side effects. If you've been taking steroid tablets for more than a few days, you usually need to reduce your dose gradually. Stopping suddenly can cause your adrenal gland, which makes important hormones for the body, to stop working.

This is known as adrenal insufficiency. Your doctor will be able to provide more advice about how to safely stop taking steroids. Taking steroid tablets for less than 3 weeks is unlikely to cause any significant side effects. But you may get some side effects if you need to take them for longer or at a high dose. Most side effects will pass once treatment stops. Tell your doctor if they bother you.

You can report any suspected side effect to the UK Yellow Card safety scheme. Your doctor may reduce your dose or suggest taking your tablets less often for example, every other day if you're having side effects.

They may also sometimes recommend other medicines to take alongside steroids to protect you from some of the side effects, such as medicines to help prevent indigestion or heartburn, or medicines that help strengthen the bones. You may be given a special steroid treatment card that explains how you can reduce the risk of side effects.

Some medicines interfere with the way steroid tablets work. Tell your doctor if you take any other medicines, including herbal remedies and supplements, before starting steroid tablets. If you're already taking steroid tablets, ask your doctor or a pharmacist for advice before taking any other medicines, remedies or supplements. You can usually drink alcohol while taking steroid tablets, but do not drink too much as this may irritate your stomach. You can also eat most foods while taking steroid tablets.

Do not eat liquorice while taking prednisolone, however, as this can increase the amount of the medicine in your body. Steroid tablets may not be suitable in these cases, although your doctor may recommend them if they think the benefits outweigh any risks. Steroid tablets are not usually recommended for children as they can cause growth problems. Steroids are a manmade version of hormones normally produced by the adrenal glands, which are 2 small glands found above the kidneys.

When taken in doses higher than the amount your body normally produces, steroids reduce redness and swelling inflammation.

This can help with inflammatory conditions such as asthma and eczema. Steroids also reduce the activity of the immune system, the body's natural defence against illness and infection. This can help treat autoimmune conditions, such as rheumatoid arthritis or lupus , which are caused by the immune system mistakenly attacking the body. Steroid tablets are different from the anabolic steroids used illegally by some people to increase their muscle mass.

Page last reviewed: 17 January Next review due: 17 January Steroid tablets. Common examples include: prednisolone betamethasone dexamethasone hydrocortisone How and when to take steroid tablets Take your medicine as instructed by your doctor. If you miss a dose or take too much If you forget a dose, take it as soon as you remember. Do not take a double dose to make up for a forgotten dose. Coming off treatment Do not stop taking your medicine without talking to your doctor.

Symptoms of adrenal insufficiency include: feeling extremely tired feeling and being sick dizziness loss of appetite and weight loss Your original symptoms may also come back suddenly. Side effects of steroid tablets Taking steroid tablets for less than 3 weeks is unlikely to cause any significant side effects. Side effects of steroid tablets can include: indigestion or heartburn increased appetite, which could lead to weight gain difficulty sleeping changes in mood and behaviour, such as feeling irritable or anxious an increased risk of infections — especially chickenpox , shingles and measles high blood sugar or diabetes weakening of the bones osteoporosis high blood pressure Cushing's syndrome — which can cause symptoms such as thin skin that bruises easily, a build-up of fat on the neck and shoulders and a red, puffy, rounded face eye conditions, such as glaucoma and cataracts mental health problems, such as depression or suicidal thoughts ; get an urgent GP appointment or call if this happens Most side effects will pass once treatment stops.

Coping with side effects of steroid tablets The following tips may help reduce the side effects of steroid tablets: take your tablets in the morning with breakfast although some specially coated tablets can be taken without food — this may help prevent indigestion, heartburn and sleeping difficulties eat a healthy, balanced diet and exercise regularly — this may help prevent weight gain and osteoporosis avoid close contact with people who are ill; especially people who have measles, chickenpox or shingles — get medical advice as soon as possible if you think you may have been exposed to someone with an infection ensure your vaccines are up-to-date — but do not have any "live" vaccines , such as the shingles vaccine Your doctor may reduce your dose or suggest taking your tablets less often for example, every other day if you're having side effects.

Taking steroid tablets with other medicines, food or alcohol Some medicines interfere with the way steroid tablets work. Who can take steroid tablets Most people can take steroid tablets. Tell your doctor before starting treatment if you: have had an allergic reaction to steroids in the past have an infection including eye infections you have recently had, or are about to have, any vaccinations have an open wound that has not healed yet are pregnant, breastfeeding or trying for a baby have any other conditions, such as diabetes, epilepsy , high blood pressure, or problems with your liver, heart or kidneys Steroid tablets may not be suitable in these cases, although your doctor may recommend them if they think the benefits outweigh any risks.

How steroid tablets work Steroids are a manmade version of hormones normally produced by the adrenal glands, which are 2 small glands found above the kidneys.

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Steroids such as prednisone. Prednisone



  Your doctor will be able to provide more advice about how to safely stop taking steroids. If you want to check your medicines are safe to take with corticosteroids, ask your GP or pharmacist, or read the patient information leaflet that comes with your medicine. What should I know about storage and disposal of this medication? Taking steroid tablets with other medicines, food or alcohol Some medicines interfere with the way steroid tablets work. If you're already taking steroid tablets, ask your doctor or a pharmacist for advice before taking any other medicines, remedies or supplements. You can report any suspected side effect to the Yellow Card Scheme.     ❾-50%}

 

Steroids such as prednisone.Steroid tablets



    These circumstances include:. Live vaccines Some vaccinations contain a weakened form of the infection they are designed to protect against. Reprint Permissions A single copy of these materials may be reprinted for noncommercial personal use only. Elsevier;

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Types of medicine. Corticosteroids, often known as steroids, are an anti-inflammatory medicine prescribed for a wide range of conditions.

They're a man-made version of hormones normally produced by the adrenal glands two small glands that sit on top of the kidneys. Corticosteroids can also be used to replace certain hormones that are not being produced by the body naturally — for example, in people with Addison's disease. Corticosteroids will only be prescribed if the potential benefits of treatment outweigh the risks. They will also be prescribed at the lowest effective dose for the shortest possible time. There aren't usually any severe side effects if you take steroid injections, a steroid inhaler, or a short course of steroid tablets.

However, prolonged treatment at high doses — particularly with steroid tablets — can cause problems in some people. If you have troublesome side effects after taking corticosteroids, don't stop taking your medication until your doctor says it's safe to do so, because of the possibility of these unpleasant withdrawal effects. Your dose may need to be reduced slowly over a few weeks or months, and you may have to have tests to ensure that your adrenal glands are still working properly before stopping corticosteroids altogether, if you have been taking them for a long time.

Read more about the side effects of corticosteroids. For most people, including pregnant or breastfeeding women, steroid inhalers and injections are safe. However, they will still only be used if a doctor thinks the potential benefits outweigh the risks. As steroid tablets are more likely to cause side effects, there are some circumstances when they shouldn't be used or should only be used with caution.

These circumstances include:. Read more about who can use corticosteroids and interactions of corticosteroids. Visit our self-help guide on accessing medicines if you have difficulty getting the medicines you need. For most people, steroid inhalers and steroid injections should not cause any troublesome side effects. Steroid tablets are generally prescribed with more caution, as these can potentially cause more problems. Corticosteroid tablets are the most powerful type of steroid medication, because they can affect the whole body.

They shouldn't be used if you have an ongoing widespread infection, because they could make it more severe. However, you should continue to take corticosteroids if you develop an infection while already being treated, unless advised otherwise. They should also be used with caution in people with a health condition that could be made worse by taking oral corticosteroids, including:. In these situations, you will only be prescribed oral corticosteroids if the benefits of treatment clearly outweigh any potential risks.

Most people can safely have corticosteroid injections, but they should be avoided or used with caution if you have an ongoing infection or a blood clotting disorder such as haemophilia. There is generally no reason why someone shouldn't be able to use a steroid inhaler or steroid spray, but these should be used with caution in people with ongoing infections, such as tuberculosis TB. Corticosteroids are generally safe to use during pregnancy. However, they're not usually recommended unless the potential benefits outweigh the risks.

For example, steroid tablets may be recommended if you're pregnant and have severe asthmabecause the risk to your baby from uncontrolled asthma is higher than from the medication. There is no evidence that using a steroid inhaler during pregnancy increases the risk of problems such as birth defects, so you can usually continue to use this as normal while you're pregnant. If a woman needs to take steroid tablets while she is breastfeeding, a type called prednisolone is usually recommended, because it is thought to have the least chance of causing the baby any adverse effects.

As a precaution, it's usually recommended that a breastfeeding mother waits three to four hours after taking a tablet before feeding her baby. Steroid injections, inhalers and sprays are not thought to pose a risk to babies being breastfed. Corticosteroids can interact with other medicines, and the effects of either medicine can be altered as a result.

There is less chance of this happening with steroid injections or sprays, although it can occasionally happen if they're used at high doses and for a long time. Some of the more common interactions are listed below, but this is not a complete list. If you want to check your medicines are safe to take with corticosteroids, ask your GP or pharmacist, or read the patient information leaflet that comes with your medicine.

Anticoagulant medicines are medications that make the blood less sticky. They are often prescribed to people with a history of blood clots or an increased risk of developing them. Combining corticosteroids with anticoagulant medicines can sometimes make anticoagulants less effective.

Alternatively, it can increase their blood-thinning effect, which can cause bleeding inside the digestive system. Anticonvulsants are medicines used to prevent seizures fits and are often used to treat epilepsybut they can reduce the effectiveness of corticosteroids.

Depending on how frequent and severe your seizures are and the condition the steroids are being used to treat, you may be advised to temporarily stop taking anticonvulsants. Corticosteroids can decrease the effectiveness of medications used to treat diabetes. If you need to take both of these medications, your blood glucose levels will usually be checked more regularly and your dose of diabetes medication may need to be adjusted.

Corticosteroids, including steroid inhalers, can sometimes interact with a type of medication known as protease inhibitors such as ritonavir used to treat HIV. The HIV medication may increase the level of corticosteroid in your body, which might increase your risk of experiencing side effects.

Some vaccinations contain a weakened form of the infection they are designed to protect against. These are known as live vaccines. Examples of live vaccines include:. As corticosteroids can weaken your immune system and make you more vulnerable to infection, you should avoid any live vaccine until at least three months after your course of corticosteroids has finished. Non-steroidal anti-inflammatory drugs NSAIDs are a group of commonly used painkillers, such as ibuprofenthat are available over the counter at pharmacists.

Combining NSAIDs and corticosteroids can increase your risk of developing stomach ulcers and internal bleeding. If you need to take both medications, you may be given an additional medication called a proton pump inhibitor PPI to reduce the risk of stomach ulcers. Some of the main side effects are listed below, but this is not a complete list.

To learn about all the possible side effects of your medication, read the patient information leaflet that comes with it.

Inhaled steroids usually have few or no side effects if used at normal doses. However, they can sometimes cause:. Rinsing your mouth out with water after using your medication can help to prevent oral thrush, and using a device called a spacer with your medication can help to prevent many of the other problems. There is also some evidence that steroid inhalers used by people with chronic obstructive pulmonary disease COPD can increase the risk of chest infections such as pneumonia.

Inhaled steroids at high doses can sometimes cause some of the more serious side effects that are more often linked with steroid tablets see belowbut this is rare. Steroids that are injected into muscles and joints may cause some pain and swelling at the site of the injection.

However, this should pass within a few days. Steroid injections can also cause muscle or tendon weakness, so you may be advised to rest the treated area for a few days after the injection. Other possible side effects can include infections, blushing, and thinning and lightening of the skin in the area where the injection is given. Because of the risk of side effects, steroid injections are often only given at intervals of at least 6 weeks and a maximum of 3 injections into one area is usually recommended.

Steroids that are injected into a blood vessel intravenous steroids may sometimes cause some of the more widespread side effects described below. Short, occasional courses of steroid tablets taken for no longer than three weeks are very unlikely to cause troublesome side effects. Most side effects should improve if you're able to reduce your dosage or eventually stop taking the medication. You may have regular checks and tests for conditions such as diabetes, high blood pressure and glaucoma if you need to take steroid tablets on a long-term basis.

Source: NHS 24 - Opens in new browser window. Last updated: 07 January Home Tests and treatments Medicines and medical aids Types of medicine Types of medicine. Corticosteroids See all parts of this guide Hide guide parts 1.

Introduction 2. Who can use them 3. Medicines that interact with them 4. Side effects. Introduction Corticosteroids, often known as steroids, are an anti-inflammatory medicine prescribed for a wide range of conditions. Corticosteroids are available in different forms, including: tablets oral steroids injections — which can be into blood vessels, joints or muscles inhalers — such as mouth or nasal sprays lotions, gels or creams topical steroids What are corticosteroids used for?

Corticosteroids are mainly used to reduce inflammation and suppress the immune system. They are used to treat conditions such as: asthma allergic rhinitis and hay fever urticaria hives atopic eczema chronic obstructive pulmonary disease COPD painful and inflamed joints, muscles and tendons lupus inflammatory bowel disease IBD — including Crohn's disease and ulcerative colitis giant cell arteritis and polymyalgia rheumatica multiple sclerosis MS Corticosteroids can also be used to replace certain hormones that are not being produced by the body naturally — for example, in people with Addison's disease.

Possible side effects Corticosteroids will only be prescribed if the potential benefits of treatment outweigh the risks. Potential side effects of long-term treatment include: increased appetite — potentially leading to weight gain acne thinned skin that bruises easily increased risk of infections mood changes, mood swings and depression diabetes high blood pressure osteoporosis weak and brittle bones withdrawal symptoms caused by suppression of the adrenal glands If you have troublesome side effects after taking corticosteroids, don't stop taking your medication until your doctor says it's safe to do so, because of the possibility of these unpleasant withdrawal effects.

Cautions and interactions For most people, including pregnant or breastfeeding women, steroid inhalers and injections are safe. Accessing medicines self-help guide Visit our self-help guide on accessing medicines if you have difficulty getting the medicines you need. Who can use them For most people, steroid inhalers and steroid injections should not cause any troublesome side effects. Steroid tablets Corticosteroid tablets are the most powerful type of steroid medication, because they can affect the whole body.

Steroid tablets should be used with caution in people with: liver problems, such as liver disease — corticosteroids may not be broken down by the liver at a normal rate, leading to increased levels of the medication in the blood mental health or behavioural problems, such as depression or alcohol dependence — corticosteroids can have unpredictable effects on behaviour and mood wounds — oral corticosteroids can delay wound healing They should also be used with caution in people with a health condition that could be made worse by taking oral corticosteroids, including: heart failure a recent heart attack high blood pressure diabetes epilepsy glaucoma underactive thyroid gland osteoporosis obesity psychosis stomach ulcers In these situations, you will only be prescribed oral corticosteroids if the benefits of treatment clearly outweigh any potential risks.

Steroid injections Most people can safely have corticosteroid injections, but they should be avoided or used with caution if you have an ongoing infection or a blood clotting disorder such as haemophilia. Steroid inhalers and sprays There is generally no reason why someone shouldn't be able to use a steroid inhaler or steroid spray, but these should be used with caution in people with ongoing infections, such as tuberculosis TB. Pregnancy Corticosteroids are generally safe to use during pregnancy.

Breastfeeding If a woman needs to take steroid tablets while she is breastfeeding, a type called prednisolone is usually recommended, because it is thought to have the least chance of causing the baby any adverse effects.

Medicines that interact with them Corticosteroids can interact with other medicines, and the effects of either medicine can be altered as a result.

Anticoagulant medicines Anticoagulant medicines are medications that make the blood less sticky. Anticonvulsants Anticonvulsants are medicines used to prevent seizures fits and are often used to treat epilepsybut they can reduce the effectiveness of corticosteroids.

Diabetes medication Corticosteroids can decrease the effectiveness of medications used to treat diabetes. HIV medication Corticosteroids, including steroid inhalers, can sometimes interact with a type of medication known as protease inhibitors such as ritonavir used to treat HIV. Live vaccines Some vaccinations contain a weakened form of the infection they are designed to protect against.

localhost › content › what-you-need-know-about-prednisone. Corticosteroid drugs — including cortisone, hydrocortisone and prednisone — are useful in treating many conditions, such as rashes, inflammatory bowel. Prednisone is in a class of medications called corticosteroids. It works to treat patients with low levels of corticosteroids by replacing. Corticosteroid drugs — including cortisone, hydrocortisone and prednisone — are useful in treating many conditions, such as rashes, inflammatory bowel. Prednisone belongs to a class of drugs known as corticosteroids. It decreases your immune system's response to various diseases to reduce symptoms such as. Drug allergy Dust mite allergy Ease rheumatoid arthritis pain when grocery shopping Ease stress to reduce eczema symptoms Eczema bleach bath: Can it improve my symptoms? Take prednisone exactly as directed. Products and services. Inhaled steroids at high doses can sometimes cause some of the more serious side effects that are more often linked with steroid tablets see belowbut this is rare. For most people, steroid inhalers and steroid injections should not cause any troublesome side effects. Steroid tablets Short, occasional courses of steroid tablets taken for no longer than three weeks are very unlikely to cause troublesome side effects.

Corticosteroid drugs — including cortisone, hydrocortisone and prednisone — are useful in treating many conditions, such as rashes, inflammatory bowel disease and asthma. But these drugs also carry a risk of various side effects. When prescribed in doses that exceed your body's usual levels, corticosteroids suppress inflammation. This can reduce the signs and symptoms of inflammatory conditions, such as arthritis, asthma or skin rashes.

Corticosteroids also suppress your immune system, which can help control conditions in which your immune system mistakenly attacks its own tissues. Corticosteroid drugs are used to treat rheumatoid arthritis, inflammatory bowel disease IBD , asthma, allergies and many other conditions. These drugs also help suppress the immune system in order to prevent organ rejection in transplant recipients.

Corticosteroids also treat Addison's disease, a relatively rare condition where the adrenal glands aren't able to produce even the minimum amount of corticosteroid that the body needs. Corticosteroids are administered in many different ways, depending on the condition being treated:. Corticosteroids carry a risk of side effects, some of which can cause serious health problems. When you know what side effects are possible, you can take steps to control their impact.

Because oral corticosteroids affect your entire body instead of just a particular area, this route of administration is the most likely to cause significant side effects. Side effects depend on the dose of medication you receive and may include:.

When using an inhaled corticosteroid, some of the drug may deposit in your mouth and throat instead of making it to your lungs. This can cause:. If you gargle and rinse your mouth with water — don't swallow — after each puff on your corticosteroid inhaler, you may be able to avoid mouth and throat irritation. Some researchers have speculated that inhaled corticosteroid drugs may slow growth rates in children who use them for asthma. Injected corticosteroids can cause temporary side effects near the site of the injection, including skin thinning, loss of color in the skin, and intense pain — also known as post-injection flare.

Other signs and symptoms may include facial flushing, insomnia and high blood sugar. Doctors usually limit corticosteroid injections to three or four a year, depending on each patient's situation. Corticosteroids may cause a range of side effects. But they may also relieve the inflammation, pain and discomfort of many different diseases and conditions.

Talk with your doctor to help you better understand the risks and benefits of corticosteroids and make informed choices about your health. There is a problem with information submitted for this request. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID, plus expertise on managing health. To provide you with the most relevant and helpful information, and understand which information is beneficial, we may combine your email and website usage information with other information we have about you.

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Elsevier; Accessed Oct. Grennan D, et al. Steroid side effects. Saag KG, et al. Major side effects of systemic glucocorticoids. Major side effects of inhaled glucocorticoids. Roberts WN, et al.

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